WHO Declares Ebola Emergency – Access Free Research Now | For Researchers

The WHO has declared a Public Health Emergency of International Concern (PHEIC) in relation to an outbreak of Ebola Disease caused by the Bundibugyo virus.

There are currently no widely licensed vaccines or specific therapeutics for this virus. In line with Springer Nature’s established approach to supporting the sharing of research during public health emergencies, we are making a broad body of recent and relevant Ebola research freely available to support the global response to the current outbreak.

Below are some examples of this research published in our journals, as well as additional commentary on this topic and relevant books. You can search for additional content on Springer Nature Link.

Springer Nature encourages early sharing of research submitted to our journals through preprints, and our In Review preprint service is available for many journals.

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Building a case for accelerated clinical development of drugs and vaccines – what are the driving forces?

from Globalization and Health

Development of an immunochromatographic lateral flow assay for the rapid detection of all known orthoebolavirus glycoproteins

from npj Viruses

Access to licenced vaccines for high-threat infectious diseases: a scoping review and interpretive analysis of Ebola virus disease

from BMC Infectious Diseases

Early transcriptomic signature of the immune response to rVSV∆G-ZEBOV-GP vaccination in Gabonese children

from npj Vaccines

Bundibugyo Ebola without vaccines or therapeutics: why public health fundamentals matter more than border closures

from Nature Medicine

Infection prevention and control measures for Ebola disease and their outcomes from the perspective of health care workers: a mixed-methods study

from BMC Public Health

Epidemiological characteristics, clinical manifestations, and treatment outcome of 139 paediatric Ebola patients treated at a Sierra Leone Ebola treatment center

from BMC Infectious Diseases

Impacts of environmental and socio-economic factors on emergence and epidemic potential of Ebola in Africa

from Nature Communications

Evaluation of contact tracing performance during an Ebola virus disease outbreak in a complex security environment: the case of North Kivu province, Democratic Republic of the Congo, 2018–2020

from Conflict and Health

The devil’s in the detail: an appraisal of the use of innovative financing mechanisms for pandemic prevention, preparedness and response

from Globalization and Health

Structural basis of broad ebolavirus neutralization by a human survivor antibody

from Nature Structural & Molecular Biology

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

from Nature Microbiology

Impact of most promising Ebola therapies on survival: a secondary analysis during the tenth outbreak in the Democratic Republic of Congo

from Virology Journal

A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies

from npj Viruses

Symptoms and determinants of post-traumatic stress disorder and psychological distress among adolescents in Ebola virus disease affected areas: a longitudinal design

from European Child & Adolescent Psychiatry

Development of VP30-targeted nanoparticles using DPS4 fusion peptides for the inhibition of Ebola virus

from Journal of Nanobiotechnology

Improved VSV-Ebola-GP booster vaccination approach promotes antibody affinity maturation and durable anti-Ebola immunity in humans

from Nature Immunology

A Phase Ia randomised double-blinded placebo-controlled study of a Bundibugyo virus disease vaccine, ChAdOx1 Ebola BDBV Vaccine (Recombinant), in healthy volunteers aged 18–55 years in the UK	Hemorrhagic Fever Viruses
Building resilient systems for Ebola outbreak prevention and preparedness	Emerging viruses and pandemic threats
Infectious disease modelling for health policy	Virus, microbe, parasite interactions shaping infection across host and vector
Therapeutic strategies to target the Ebola virus life cycle	Recognition of aerosol transmission of infectious agents: a commentary
A Year In, the Second-Largest Ebola Outbreak Continues to Rage	The role of low-density lipoprotein receptors in emerging and reemerging viruses: a review with examples from human metapneumovirus and beyond
Maternal and Infant Death and the rVSV-ZEBOV Vaccine Through Three Recent Ebola Virus Epidemics-West Africa, DRC Équateur and DRC Kivu: 4 Years of Excluding Pregnant and Lactating Women and Their Infants from Immunization	Ebola vaccine safe for mothers and infants
PARTNERS trial	Durable humoral immunity and long-term protection induced by a Crimean-Congo hemorrhagic fever virus replicon particle vaccine in mice
How Rwanda mounted a research response with an investigational vaccine just ten days into a Marburg outbreak	Ebola can be stopped — but only if world leaders prioritize public health
Ebola Economics: The Case for an Upstream Approach to Disease Emergence	In Liberia, the End of the Ebola Epidemic will be the Beginning

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